New Hope for Diabetes Patients in Latest Study
The problem of diabetes is a daily struggle for more than 29 million Americans, a number that is steadily increasing. The inability to efficiently process sugar – called insulin resistance – is at the root of what is called Type 2 Diabetes, the most common form.
A new study, reported online in Nature Medicine, holds promise of new insights into this problem and hope for these individuals. Perelman School of Medicine at the University of Pennsylvania sponsored the research, and the team reports finding a new link between the presence of particular amino acids and the occurrence of Type 2 Diabetes.
Researchers used muscle and blood samples from both mice and humans to explore the way insulin resistance develops and affects patients. Most patients are aware that the problem with diabetes is directly related to blood sugar levels, calling for frequent monitoring and managing of those levels. However, fewer understand that it is also a problem of excess fat in the body, especially within skeletal muscle.
The study’s results included identifying ways that 3-HB, produced when amino acids breakdown, may be one pathway by which the body produces more fat and creates insulin resistance. It is hoped this promising area of study will produce new ways to target treatment.