New Study Reveals How a High-Fat Meal Affects Your Liver

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Source: The Sun

Researchers know that people who regularly eat high-fat meals tend to develop a variety of health problems.  One specific health condition that develops is non-alcoholic fatty liver disease (NAFLD), but the link as to why is unclear.  NAFLD leads to liver inflammation and most commonly affects those ages 40 to 50, and causes permanent liver damage.  A new study published in The Journal of Clinical Investigation, researchers studied this phenomenon at a molecular level following a single high-fat meal in 14 lean and healthy male participants and an equal number of male mice.

Following a single meal with a quantity of palm oil, they looked at each participant’s liver metabolism.  Researchers found an increase in hepatic triglycerides by 35%, a decrease in insulin sensitivity overall by 25%, and an increase of glucagon (the hormone that increases glucose levels) in their bloodstream immediately following the high-fat meal.  This means that high-fat meals influence the liver metabolism in a way that leads to fat storage and lays a foundation for metabolic diseases that can lead to NAFLD and other health problems.


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